Abstract
Introduction: It is lived in a society where the media induces our patient's standards of aesthetics and beauty. Patients are seeking more and more offices for a completely aesthetic smile. Toothpaste whiteners consist of surfactants, polyphosphates, enzymes, peroxides, citrate, pyrophosphate, hexametaphosphate, blue covarine, and abrasive agents. Objective: It was to conduct a systematic review to present the main considerations and outcomes of clinical studies on dental bleaching. Methods: The PRISMA Platform systematic review rules were followed. The search was carried out from July to August 2025 in the Scopus, Embase, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument, and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 175 articles were found, and 40 articles were evaluated in full, and 30 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 30 studies with a high risk of bias and 25 that did not meet the GRADE and AMSTAR-2 criteria. According to the GRADE instrument, most studies presented homogeneity in their results, with X2=94.7%>50%. It was concluded that after analyzing and comparing the literature results obtained before and after the use of toothpastes and mouthwashes, it can be observed that the products did not promote teeth bleaching. Also, external root resorption in internal tooth whitening is one of the disadvantages of whitening; the etiology is unknown. External cervical resorption is the loss of hard tissue of the dental structure, such as cementum and dentin, resulting in an odontoclastic action, its onset usually occurring in the cervical region of the root surface, and is asymptomatic.