Skip to main content Skip to main navigation menu Skip to site footer
MedNext Journal of Medical and Health Sciences
Review
DOI: 10.34256/mdnt21212
Submitted: 16-09-2021
Published: 12-05-2021

Intestinal Failure and Short Bowel Syndrome in Crohn’s Disease: A Systematic Review

Nutritional Therapy at the Santa Isabel Hospital, Blumenau, Santa Catarina, Brazil
ABRAN - Associação Brasileira de Nutrologia /Brazilian Association of Nutrology, Catanduva/SP, Brazil
ABRAN - Associação Brasileira de Nutrologia /Brazilian Association of Nutrology, Catanduva/SP, Brazil
Intestinal failure Short bowel syndrome Crohn's disease Nutritional support

Abstract

Crohn's disease (CD) is an inflammatory, chronic and progressive disease that affects the digestive tract. Despite optimized drug therapy, the risk of multiple surgical interventions over the years is high, leading the patient to develop short bowel syndrome (SBS). Thus, adequate management in the postoperative period directly interferes with the long-term prognosis. Initially, most of these patients, due to hydro electrolytic disorders and absorptive incapacity inherent in SBS, will need parenteral nutritional support. According to the patient's residual digestive profile and according to nutritional management (oral, enteral, and/or parenteral), the intestine will evolve in its adaptive capacity. During this period, control agents are used for motility and intestinal secretion and, if necessary, GLP-2 agonists (intestinotrophic). In cases refractory to these treatments, we can still indicate surgical procedures to control motility, increasing intestinal length, and, finally, transplantation. CD is recurrent, and patients with SBS need a multidisciplinary approach with continuous monitoring to provide better intestinal rehabilitation and consequent quality of life.

Metrics

Metrics Loading ...

References

  1. J. Torres, S. Mehandru, J.F. Colombel, L. Peyrin-Biroulet, Crohn's disease, Lancet, 389 (2017) 1741-1755.
  2. B.N. Limketkai, A.M. Parian, N.D. Shah, J.F. Colombel, Short Bowel Syndrome and Intestinal Failure in Crohn's Disease, Inflammatory Bowel Disease, 22 (2016) 1209-1218.
  3. P. Drastich, M. Oliverius, Crohn’s Disease and Intestinal Transplantation, Digestive Diseases and Sciences, 35 (2017) 127-133.
  4. Steven Jeuring, Tim Van den Heuvel, Maurice Zeegers, Wim Hameeteman, Mariëlle Romberg-Camps, Liekele E. Oostenbrug, Stéphanie O Breukink, Laurents P S Stassen, Wim H Hameeteman, Ad A M Masclee, Daisy M A E Jonkers, Marieke J Pierik, Disease Outcome of Ulcerative Colitis in an Era of Changing Treatment Strategies: Results from the Dutch Population-Based IBDSL Cohort, Journal of Crohn's and Colitis, 9 (2015) 837-845.
  5. D. Sorrentino, S. Fogel, J. Van den Bogaerde, Surgery for Crohn's disease and anti-TNF agents: the changing scenario, Expert Review of Gastroenterology & Hepatology, 7 (2013) 689-700.
  6. D. Moher, A. Liberati, J. Tetzlaff, D.G. Altman, The PRISMA Group, Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement, PLOS Medicine, 6 (2009) 1-6.
  7. Howard Balshem, Mark Helfand, Holger J Schünemann, Andrew D Oxman, Regina Kunz, Jan Brozek, Gunn E Vist, Yngve Falck-Ytter, Joerg Meerpohl, Susan Norris, Gordon H Guyatt, Grade guidelines: 3 ratng the quality of evidence, Journal of Clinical Epidemiology, 64 (2011) 401-406.
  8. J. Higgins, S. Green, (2011) Cochrane Handbook for Systematic Reviews of Interventions, The Cochrane Collaboration.
  9. Paulo Gustavo Kotze, Fox E Underwood, Aderson Omar Mourão Cintra Damião, Jose Geraldo P Ferraz, Rogerio Saad-Hossne, Martin Toro, Beatriz Iade, Francisco Bosques-Padilla, Fábio Vieira Teixeira, Fabian Juliao-Banos, Daniela Simian, Subrata Ghosh, Remo Panaccione, Siew C Ng, Gilaad G Kaplan, Progression of Inflammatory Bowel Diseases Throughout Latin America and the Caribbean: a Systematic Review, Clinical Gastroenterology and Hepatology, 18 (2020) 304-312
  10. A. Forbes, Crohn’s disease: rehabilitation after resection, Digestive Diseases, 32 (2014) 395-398.
  11. M.S. Mundi, A. Pattinson, M.T. McMahon, J. Davidson, R.T. Hurt, Prevalence of Home Parenteral and Enteral Nutrition in the United States, Nutrition in Clinical Practice, 32 (2017) 799-805.
  12. Augusto Lauro, Francesco, D’Amico, Gabriel Gondolesi, The current therapeutic options for Crohn's disease: from medical therapy to intestinal transplantation, Expert Review of Gastroenterology & Hepatology, 11 (2017) 1105-1117.
  13. Loris Pironi, Jann Arends, Janet Baxter, Federico Bozzetti, Rosa Burgos Peláez, Cristina Cuerda, Alastair Forbes, Simon Gabe, Lyn Gillanders, Mette Holst, Palle Bekker Jeppesen, Francisca Joly, Darlene Kelly, Stanislaw Klek, Øivind Irtun, S W Olde Damink, Marina Panisic, Henrik Højgaard Rasmussen, Michael Staun, Kinga Szczepanek, André Van Gossum, Geert Wanten, Stéphane Michel Schneider, Jon Shaffer, Home, ESPEN endorsed recommendations, Definition and classification of intestinal failure in adults, Clinical Nutrition, 34 (2015) 171-80.
  14. P. Drastich, M. Oliverius, Crohn’s Disease and Intestinal Transplantation, Digestive Diseases, 35 (2017) 127-133.
  15. Loris Pironi, Jann Arends, Federico Bozzetti, Cristina Cuerda, Lyn Gillanders, Palle Bekker Jeppesen, Francisca Joly, Darlene Kelly, Simon Lal, Michael Staun, Kinga Szczepanek, André Van Gossum, Geert Wanten, Stéphane Michel Schneider, ESPEN guidelines on chronic intestinal failure in adults, Clinical Nutrition, 35 (2016) 247-307.
  16. R.E. Carroll, E. Benedetti, J.P. Schowalter, A.L. Buchman, Management and Complications of Short Bowel Syndrome: An Updated Review, Current Gastroenterology Reports, 18 (2016) 40.
  17. Klek S, Forbes A, Gabe S, Holst M, Wanten G, Irtun Ø, Damink SO, et al. Management of acute intestinal failure: A position paper from the European Society for Clinical Nutrition and Metabolism (ESPEN) Special Interest Group, Clinical Nutrition, 35 (2016) 1209-1218.
  18. K.A. Tappenden, Mechanisms of enteral nutriente enhanced intestinal adaptation, Gastroenterology, 130 (2006) 93-99.
  19. S. Fruhwald, P. Holzer, H. Metzler, Intestinal motility disturbances in intensive care patients pathogenesis and clinical impact, Intensive Care Medicine, 33 (2007) 36-44.
  20. Renée Blaauw, Emma Osland, Krishnan Sriram, Azmat Ali, Johane P Allard, Patrick Ball, Lingtak-Neander Chan, Brian Jurewitsch, Kathleen Logan Coughlin, William Manzanares, Ana Maria Menéndez, Rina Mutiara, Ricardo Rosenfeld, Marianna Sioson, Janicke Visser, Mette M Berger, Parenteral Provision of Micronutrients to Adult Patients: An Expert Consensus Paper, Journal of Parenteral and Enteral Nutrition, 43 (2019) 5-23.
  21. R. Even Dar, Y. Mazor, A. Karban, S. Ish-Shalom, E. Segal, Risk Factors for Low Bone Density in Inflammatory Bowel Disease: Use of Glucocorticoids, Low Body Mass Index, and Smoking, Digestive Diseases, 37 (2019) 284-290.
  22. Alastair Forbes, Johanna Escher, Xavier Hébuterne, Stanisław Kłęk, Zeljko Krznaric, Stéphane Schneider, Raanan Shamir, Kalina Stardelova, Nicolette Wierdsma, Anthony E Wiskin, Stephan C Bischoff, ESPEN guideline: Clinical nutrition in inflammatory bowel disease, Clinical Nutrition, 36 (2017) 321-347.
  23. G.C. Curhan, E.M. Taylor, 24-h uric acid excretion and the risk of kidney stones, Kidney International, 73 (2008) 489-496.

How to Cite

Boemer, H. T., Garcia Ramirez, A. V., & Ribas Filho, D. (2021). Intestinal Failure and Short Bowel Syndrome in Crohn’s Disease: A Systematic Review. MedNEXT Journal of Medical and Health Sciences, 2(2), 77–86. https://doi.org/10.34256/mdnt21212