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Review
Published: 08-08-2023

Relationship between periodontal disease in pregnant women and premature birth: a comprehensive review

UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil
UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil
UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil
UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil / UNIPOS - Post graduate and continuing education, Dentistry department, São José do Rio Preto, São Paulo, Brazil
Periodontal disease Premature birth Low weight at birth

Abstract

Initially, it should be noted that the birth of premature babies constitutes the fundamental cause of morbidity and mortality and morbidity soon after birth. There are several factors that imply risks and are directly related to its development, such as the use of psychoactive substances, infections of the genito-urinary tract and tobacco. smoke and other infections at a distance. Periodontal disease is considered an independent risk factor for premature low birth weight babies, which places active periodontal disease as an independent risk factor for the birth of premature and low birth weight babies. In this perspective, the objective of this work is to analyze periodontal disease as a risk factor for prematurely born babies. The methodology used in the development of the work is the literature review, with the use of articles from reference periodicals for the theme. It can be stated that in cases of periodontal disease, inflammatory stimuli can induce hyperirritability of the uterine smooth muscle, causing contraction of the uterus and cervical dilation, triggering premature birth. By constituting a chronic infection, it can influence the occurrence of premature birth indirectly or directly. However, it is important to understand that the treatment of periodontal disease is effective, reducing the incidence of premature birth.

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References

  1. Alves RT, Ribeiro, RA. Relationship between maternal periodontal disease and birth of preterm low weight babies. Brazilian Oral Research [online]. 2006, 20 (2) [Accessed 4 December 2022], pp. 318-323. <https://doi.org/10.1590/S180683242006000400007>. https://doi.org/10.1590/S1806-83242006000400007.
  2. Bettiol H, Barbieri MA, Silva AAM. Epidemiologia do nascimento pré-termo: tendências atuais. Rev. Bras. Ginecol. Obstet. 2010; 32(2): 57-60.
  3. Beckman I, Meise-Mikolajczy F, Leszczynsky P, Brooijmans M, Wallenburg HCS. Endotoxin-induced fetal growth retardation in the pregnant guinea pig. Am J Obstet Gynecol. 1993; 168: 714-8.
  4. Marin C, Segura-Egea JJ, Martínez-Sahuquillo Á, Bullón P. Correlation between infant birth w eight and mothers periodontal status. J Clin Periodontol. 2005; 32: 299304.
  5. Lohsoonthorn V, Kungsadalpipob K, Chanchareonsook P, Limpongsanurak S, Vanichjakvong O, Sutdhibhisal S, Sookprome C, Wongkittikraiwan N, Sookprome C, Kamolpornwijit W, Jantarasaengaram S, Manotaya S, Siwawej V, Barlow WE, Fitzpatrick AL, Williams MA. Is maternal periodontal disease a risk factor for preterm delivery? American Journal of Epidemiology. 2009; 169:731–739.
  6. Mendes, YBE et al. The influence of periodontal disease on births of premature and low birth weight children. Journal of Health Sciences, vol. 12, no. 1, 2015.
  7. Moliterno LFM, Monteiro B, Silva Figueiredo CM, Fischer RG. Association between periodontitis and low birth weight: a case-control study. J Clin Periodontol. 2005;32:886-90.
  8. MR fields. Periodontal disease as a risk factor for the birth of premature and/or low birth weight babies [Master's Thesis]. 2003; Bauru (SP): Faculty of Dentistry of Bauru, USP.
  9. Grandi C, Trungadi M, Meritano J. Maternal periodontal disease and preterm delivery: a case-control study. Rev Pan-Amaz Saude [Internet]. 2010 Jun [cited 2022 Dec 03]; 1(2) 41-48. Available at: http://scielo.iec.gov.br/scielo.php?script=sci_arttext&pid=S2176622320100002000 04&lng=pt. http://dx.doi.org/10.5123/S217662232010000200004.
  10. Lopes FF, Lima LL, Rodrigues MC, Cruz MC, Oliveira AE, Alves CM. Maternal periodontal condition and low birth weight preterm birth: case-control study. Rev Bras Ginecol Obstet 2005; 27(7): 382-6.
  11. Trentin MS; Scortegagna SA; Dal'Bello MS; De Bittencourt ME; Linden MSS; Viero R; et al. Periodontal disease in pregnant women and risk factors for preterm delivery. RFO-UPF. 2007 12(1): 47-51.
  12. Passini Junior R, Nomura ML, Politano GT. Periodontal disease and obstetric complications: is there a risk relationship? Rev Bras Ginecol Obstet. 2007; 29(7):3727.
  13. 13. Saini R, Saini S, Saini SR. Periodontitis: A risk for delivery of premature labor and low-birth-weight infants. J Nat Sci Biol Med. 2010 Jul;1(1):40-2. doi: 10.4103/0976-9668.71672.
  14. Xiong X, Buekens P, Fraser WD, Beck J, Offenbacher S. Periodontal disease and adverse pregnancy outcomes: A systematic review. BJOG Int. J. Obstet. Gynaecol. 2006; 113: 135–143.
  15. Offenbacher S, Lieff S, Boggess K A, Murtha AP, Madianos PN, Champagne CM, Mckaig RG, Jared HL Mauriello SM, Auten RL Jr, Herbert WN, Beck JD . Maternal periodontites and prematurity. Part I: Obstetric outcome of prematurity and growth restriction. Ann Periodontol. 2001; 6: 164-74.

How to Cite

Novelli, C. P., Marcos, E. M., Arakaki, P. N., & Fernandes, P. G. (2023). Relationship between periodontal disease in pregnant women and premature birth: a comprehensive review. MedNEXT Journal of Medical and Health Sciences, 4(3). https://doi.org/10.54448/mdnt23S303