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Review
Published: 22-02-2023

Main factors of bone loss and the processes of osseointegration for dental implant: a systematic review

UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil / UNIPOS - Post graduate and continuing education, Dentistry department, São José do Rio Preto, São Paulo, Brazil
UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil / UNIPOS - Post graduate and continuing education, Dentistry department, São José do Rio Preto, São Paulo, Brazil
UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil / UNIPOS - Post graduate and continuing education, Dentistry department, São José do Rio Preto, São Paulo, Brazil
UNORTE - University Center of Northern São Paulo, Dentistry department, São José do Rio Preto, São Paulo, Brazil / UNIPOS - Post graduate and continuing education, Dentistry department, São José do Rio Preto, São Paulo, Brazil
Dental implants Bone loss Saucerization Osseointegration Stability Alveolar bone

Abstract

Introduction: In the cellular, molecular and structural scenario for dental implants, primary or mechanical stability in implant dentistry is considered a prerequisite for successful osseointegration. The alveolar bone architecture of the implant drilling site dictates the success of anchored endosteal implants. Objective: It was to carry out a systematic review to highlight the main variables that can compromise bone formation and osseointegration for dental implants. Methods: The systematic review rules of the PRISMA Platform were followed. The search was carried out from October to December 2022 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases, using articles from 2010 to 2022. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 220 articles were found, and 65 articles were evaluated in full and 22 were included and developed in this systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 45 studies with a high risk of bias and 92 studies that did not meet GRADE. The success of the prosthetic restoration supported by osseointegrated implants and the health of the surrounding tissues, such as the reduction of bone loss, are closely related to the precision and adaptation of the components, the stability of the implant/abutment interface, as well as the resistance of this interface when it is subjected to loads during masticatory function. It is necessary to provide a complete understanding of the biological events that occur during osseointegration. Factors that can compromise bone healing are cholesterol, hyperlipidemia, and low vitamin D intake. Furthermore, the prominent influence of osteocytes and immune cells is influenced as being the main regulators during osseointegration and maintenance of the dental implant.

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References

  1. Pandey C, Rokaya D, Bhattarai BP. Contemporary Concepts in Osseointegration of Dental Implants: A Review. Biomed Res Int. 2022 Jun 14;2022:6170452. doi: 10.1155/2022/6170452.
  2. Ren F, Li Y, Chen L, Huang J, Tao J. The sensitivity of bone conduction for dental implants. J Acoust Soc Am. 2022 Sep;152(3):1389. doi: 10.1121/10.0013898.
  3. Maekawa S, Cho YD, Kauffmann F, Yao Y, Sugai JV, Zhong X, Schmiedeler C, Kinra N, Moy A, Larsson L, Lahann J, Giannobile WV. BMP GeneImmobilization to Dental Implants Enhances Bone Regeneration. Adv Mater Interfaces. 2022 Aug 3;9(22):2200531. doi: 10.1002/admi.202200531. Epub 2022 Jun 25.
  4. Patel V, Sadiq MS, Najeeb S, Khurshid Z, Zafar MS, Heboyan A. Effects of metformin on the bioactivity and osseointegration of dental implants: A systematic review. J Taibah Univ Med Sci. 2022 Aug 4;18(1):196-206. doi: 10.1016/j.jtumed.2022.07.003. PMID: 36398019; PMCID: PMC9643507.
  5. Hooton TA, Neill BC, Rajpara A. Single Saucerization Biopsy Technique for Blistering Diseases. J Am Acad Dermatol. 2019 Jul 25. pii: S0190- 9622(19)32449-1. doi: 10.1016/j.jaad.2019.07.059.
  6. Nevins M, Capetta E, Horning C, Kerr E, Kim DM, Kirshner K, Machell JC, Marcus E, Romanos G, Silverstein S, Strauss G, Wang HL, Winston M. Osseointegration Foundation Charity Overdenture Program Study. Int J Periodontics Restorative Dent. 2020 Mar/Apr;40(2):279-283. doi: 10.11607/prd.4531.
  7. Hoellwarth JS, Tetsworth K, Kendrew J, Kang NV, van Waes O, Al-Maawi Q, Roberts C, Al Muderis M.Periprosthetic osseointegration fractures are infrequent and management is familiar. Bone Joint J. 2020 Feb;102-B(2):162- 169. doi: 10.1302/0301-620X.102B2.BJJ-2019-0697.R2.
  8. Zhang H, Komasa S, Mashimo C, Sekino T, Okazaki J. Effect of ultraviolet treatment on bacterial attachment and osteogenic activity to alkali-treated titanium with nanonetwork structures. Int J Nanomedicine. 2017 Jun 28;12:4633-4646. doi: 10.2147/IJN.S136273. eCollection 2017.
  9. Albanese M, Ricciardi G, Donadello D, Lucchese A, Gelpi F, Zangani A, DE Santis D, Rizzini A, Rossetto A, Bertossi D. Alveolar splitting with piezosurgery, bone bank grafts and Nobelactive implants as an alternative to major bone grafting for maxillary reconstruction. Minerva Stomatol. 2017 Jul 4. doi: 10.23736/S0026-4970.17.04006-7.
  10. Weiner S, Simon J, Ehrenberg DS, Zweig B, Ricci JL. The effects of laser microtextured collars upon crestal bone levels of dental implants. Implant Dent. 2008 Jun;17(2):217-28. doi: 10.1097/ID.0b013e3181779016.
  11. Bruno F. Mello, Jefferson T. Pires, Danilo Jorge Racy, Michelini S. Trentin, Adriano Piattelli, Jamil Awad Shibli. Espaço biológico ao redor de implantes osseointegrados: uma análise fisiológica e histológica em tecido peri-implantar humano. (Int J Periodontics Restorative Dent 2016; 34:713–718.
  12. Ferrari DS, Piattelli A, Iezzi G, Faveri M, Rodrigues JA, Shibli JA. Effect of lateral static load on immediately restored implants: histologic and radiographic evaluation in dogs. Clin Oral Implants Res 2015 Apr;26(4):e51-6.
  13. Pessoa RS, Sousa RM, Pereira LM, Silva TD, Bezerra FJB, Spin-Neto R. Avaliação da estabilidade dos tecidos duros e moles em implantes imediatos com carga imediata em área estética: estudo clínico. Dental Press Implantol. 2015 Apr-Jun;9(2): 100-9.
  14. Coelho PG, Jimbo R. Osseointegration of metallic devices: current trends based on implant hardware design. Archives of biochemistry and biophysics. 2014; 561: 99-108.
  15. Coelho PG, Jimbo R, Tovar N, Bonfante EA. Osseointegration: hierarchical designing encompassing the macrometer, micrometer, and nanometer length scales. Dent Mater. 2015; 31(1): 37-52.
  16. Bezerra F, Pessoa RS, Zambuzzi WF. Carregamento funcional imediato ou precoce de implantes com câmara de cicatrização e nano-superfície: estudo clínico prospectivo longitudinal. Innov Implant J, Biomater Esthet. 2015; 9(2/3): 13-7.
  17. Insua A, Monje A, Wang HL, Miron RJ. Basis of bone metabolism around dental implants during osseointegration and peri-implant bone loss. J Biomed Mater Res A. 2017 Jul;105(7):2075-2089. doi: 10.1002/jbm.a.36060.
  18. Bazal-Bonelli S, Sánchez-Labrador L, Cortés-Bretón Brinkmann J, CoboVázquez C, Martínez-Rodríguez N, Beca-Campoy T, Santos-Marino J, Rodríguez-Fernández E, Alvarado-Lorenzo M. Influence of Serum Vitamin D Levels on Survival Rate and Marginal Bone Loss in Dental Implants: A Systematic Review. Int J Environ Res Public Health. 2022 Aug 16;19(16):10120. doi: 10.3390/ijerph191610120.
  19. Sculean A, Gruber R, Bosshardt DD. Soft tissue wound healing around teeth and dental implants. J Clin Periodontol 2014. Apr; 41 Suppl 15: S6-22.
  20. Camacho FMT, Sakamura CE, Munhoz MF, Esteves JC, Ribeiro FS, Pontes AEF. Avaliação clínica em curto prazo do sistema de Cone Morse e plataforma reduzida em prótese sobre implantes do tipo protocolo: estudo piloto randomizado. Ver Odontol Unesp. Araraquara SP. 2012; 41(4):247-53.
  21. Kim YM, Lee JB, Um HS, Chang BS, Lee JK. Long-term effect of implantabutment connection type on marginal bone loss and survival of dental implants. J Periodontal Implant Sci. 2022 Dec;52(6):496-508. doi: 10.5051/jpis.2200960048.
  22. Consolaro A., Carvalho, RS, Francischone Jr.CE, Francischone, CE. Mecanismo da saucerização nos implantes osseointegrados. Rev. Dental Press Periodont Implantol. 2010;4(1):137-54.

How to Cite

Carneiro, S. S., Flausino, L. C., Franco, N. B., & Kassis, E. N. (2023). Main factors of bone loss and the processes of osseointegration for dental implant: a systematic review. MedNEXT Journal of Medical and Health Sciences, 4(S1). https://doi.org/10.54448/mdnt23S108