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MedNext Journal of Medical and Health Sciences
Review
DOI: 10.54448/mdnt22S307
Submitted: 13-05-2022
Published: 13-05-2022

Major clinical findings of maxillary sinus surgery and the use of bio stimulators: a systematic review

UNORTE - University Center of Northern São Paulo - Dentistry department, Sao Jose do Rio Preto, Sao Paulo, Brazil - UNIPOS - Post graduate and continuing education, Dentistry department, Sao Jose do Rio Preto, Sao Paulo, Brazil
UNORTE - University Center of Northern São Paulo - Dentistry department, Sao Jose do Rio Preto, Sao Paulo, Brazil - UNIPOS - Post graduate and continuing education, Dentistry department, Sao Jose do Rio Preto, Sao Paulo, Brazil
UNORTE - University Center of Northern São Paulo - Dentistry department, Sao Jose do Rio Preto, Sao Paulo, Brazil - UNIPOS - Post graduate and continuing education, Dentistry department, Sao Jose do Rio Preto, Sao Paulo, Brazil
UNORTE - University Center of Northern São Paulo - Dentistry department, Sao Jose do Rio Preto, Sao Paulo, Brazil - UNIPOS - Post graduate and continuing education, Dentistry department, Sao Jose do Rio Preto, Sao Paulo, Brazil
Maxillary sinus surgery Biomaterials Bio stimulators Cytokines Growth factors

Abstract

Introduction: In the scenario of maxillary sinus surgery, when there is a loss of a dental element in the posterior region of the maxilla, there is natural resorption of the alveolar process and at the same time there will be pneumatization of the maxillary sinus. For this reason, the maxillary sinus floor elevation procedure should be performed. When grafting procedures are needed, our focus is often on the types of biomaterials and their bio stimulating properties, as well as on other types of bio stimulators to be used. Objective: It was to analyze the main clinical findings of maxillary sinus surgery and the use of bio stimulators through a systematic review. Methods: The present study followed a systematic review model, following the rules of systematic review – PRISMA. The search strategy was performed in the PubMed, Cochrane Library, Web of Science and Scopus, and Google Scholar databases. The present study was carried out from January to March 2022. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: After analyzing the main clinical findings on maxillary sinus surgery and the use of bio stimulators, it was concluded that bone regeneration processes using biomaterials and the main molecular and cellular constituents such as mesenchymal stem cells, cytokines, platelet-rich plasma, fibrin-rich plasma, exosomes, microRNAs, TNF-α, IL-1, LIF and IL-6 and prostaglandin E2 (PGE2) are strategic for the solution to large bone defects, leading to tissue or bone regeneration. The main filler biomaterials can be fibrin-rich plasma (FRP), Bio-Oss®. However, it is necessary to understand the chemical, physical and biological processes of both the biological material and the biological niche of the host for successful neovascularization and bone filling.

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References

  1. Bhalla N, Dym H. Update on Maxillary Sinus Augmentation. Dent Clin North Am. 2021 Jan;65(1):197-210. doi: 10.1016/j.cden.2020.09.013. Epub 2020 Nov 2. PMID: 33213709.
  2. Lenkeit CP, Lofgren DH, Shermetaro C. Maxillary Sinus Fracture. 2021 Dec 15. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 32491387.
  3. Furtado DM, Martins-Júnior PA, Alves TK, Santos RM, Coutinho DC, Neto IS, Vidigal BC, de Oliveira GA, Alves E Silva MR, Manzi FR. Prevalence and characterization of maxillary sinus septa in a brazilian population. J Clin Exp Dent. 2021 Jul 1;13(7):e642-e647. doi: 10.4317/jced.56467. PMID: 34306526; PMCID: PMC8291165.
  4. Abdel-Kader MA, Abdelazeem AF, Ahmed NEB, Khalil YM, Mostafa MI. Oral rehabilitation of a case with regional odontodysplasia using a regenerative approach-A case report and a review of literature. Spec Care Dentist. 2019, May;39(3):330-339. doi: 10.1111/scd.12378.
  5. Arab H, Shiezadeh F, Moeintaghavi A, Anbiaei N, Mohamadi S. Comparison of Two Regenerative Surgical Treatments for Peri-Implantitis Defect using Natix Alone or in Combination with Bio-Oss and Collagen Membrane. J Long Term Eff Med Implants. 2016;26(3):199-204. doi: 10.1615/JLongTermEffMedImplants.2016016396.
  6. Chiapasco M, Casentini P, Zaniboni M. Bone augmentation procedures in implant dentistry. Int J Oral Maxillofac Implants. 2009; 24 Suppl: 237-59.
  7. Choukroun J, Diss A., Simonpieri A, Girard M.O. Schhoffler C., Dohan S.L., et al.Platelet-rich-fibrin (FRP): a second generation platelet concentrate. Part IV: clinical effects on tissue healing. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod 2006: 101 (3): e 56 – 60.
  8. Diana C, Mohanty S, Chaudhary Z, Kumari S, Dabas J, Bodh R. Does platelet-rich fibrin have a role in osseointegration of immediate implants? A randomized, single-blind, controlled clinical trial. Int J Oral Maxillofac Surg. 2018 Sep;47(9):1178-1188. doi: 10.1016/j.ijom.2018.01.001. Epub 2018 May 7.
  9. Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJJ, Mouhyi J, et al. Platelet-rich-fibrin (FRP); A second generation concentrate. Part I: Tecnological concepts and evolution. Oral Sugery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology. 2006; 101 (3): e 37- e 44.
  10. Jeong SM, Lee CU, Son JS, Oh JH, Fang Y, Choi BH. Simultaneous sinus lift and implantation using platelet-rich-fibrin as sole grafting material. J. Craniomaxillofac Surgery. 2014; 42 (6): 990 – 4.
  11. Li P, Zhu H, Huang D. Autogenous DDM versus Bio-Oss granules in GBR for immediate implantation in periodontal postextraction sites: A prospective clinical study. Clin Implant Dent Relat Res. 2018 Dec;20(6):923-928. doi: 10.1111/cid.12667. Epub 2018 Sep 19.
  12. Momen-Heravi F, Peters SM, Garfinkle L, Kang P. Acellular Dermal Matrix as a Barrier for Guided Bone Regeneration of Dehiscence Defects Around Dental Implants: A Clinical and Histological Report. Implant Dent. 2018 Aug;27(4):521-524 [doi: 10.1097/ID.0000000000000796].
  13. Costa JBZ, Silva F, Dultra CA, Souza LF, Santos MCNE. Uso de membranas biológicas para regeneração óssea guiada em implantodontia – uma revisão de literatura - Revista Bahiana de Odontologia. 2016 Mar;7(1):14-21.
  14. Saghiri MA, Asatourian A, Garcia-Godoy F, Sheibani N. The role of angiogenesis in implant dentistry part II: The effect of bone-grafting and barrier membrane materials on angiogenesis. Med Oral Patol Oral Cir Bucal (2016), [doi:10.4317/medoral.21200].
  15. Mesimäki K, Lindroos B, Törnwall J, Mauno J, Lindqvist C, Kontio R, Miettinen S, Suuronen R: Novel maxillary reconstruction with ectopic bone formation by GMP adipose stem cells. Int J Oral Maxillofac Surg 2009, 38:201-209.
  16. Zotarelli Filho IJ, Frascino LF, Greco OT, Araujo JDD, Bilaqui A, Kassis EN, Ardito RV and Bonilla-Rodriguez GO. Chitosan-collagen scaffolds can regulate the biological activities of adipose mesenchymal stem cells for tissue engineering. J Regen Med Tissue Eng. 2013; 2:12. http://dx.doi.org/10.7243/2050-1218-2-12.
  17. Egido-Moreno S, Valls-Roca-Umbert J, Céspedes-Sánchez JM, López-López J, Velasco-Ortega E. Clinical Efficacy of Mesenchymal Stem Cells in Bone Regeneration in Oral Implantology. Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2021 Jan 21;18(3):894. doi: 10.3390/ijerph18030894. PMID: 33494139; PMCID: PMC7908266.
  18. Moreira AC, Silva JR, Samico RP, Nishioka GNM, Nishioka RS. Application of Bio-Oss in tissue regenerative treatment prior to implant installation: literature review. Braz Dent Sci. 22(2), 2019.
  19. Nícoli LG, Pigossi SC, Araújo RF.dSB, Marcantonio C, Marcantonio E, Marcantonio JR. E. Multidisciplinary approach to oral rehabilitation with dental implants after gunshot injury. A clinical report. The Journal of Prothestic Dentistry. 2018; 119 (3): 329 – 33.
  20. Nizam N, Eren G, Akcali A, Donos N. Maxillary sinus augmentation with leukocyte and platelet-rich fibrin and deproteinized bovine bone mineral: A split-mouth histological and histomorphometric study. Clin Oral Implants Res. 2018 Jan;29(1):67-75 [doi: 10.1111/clr.13044. Epub 2017 Aug 8].
  21. Pichotano EC, De Molon RS, Freitas De Paula LG, De Souza RV, Marcantonio E, J.R., Zandim-Barcelos, D.L. Early Placement of Dental Implants in Maxillary Sinus Grafted With Leukocyte and Platelet-Rich Fibrin and Deproteinized Bovine Bone Mineral. J Oral Implantol. 2018 Jun;44(3):199-206. doi: 10.1563/aaid-joi-D-17-00220. Epub 2018 Feb 19.
  22. Starch-Jensen, T., Aludden, H., Hallman, M., Dahlin, C., Christensen, A.E., Mordenfeld, A. A systematic review and meta-analysis of long-term studies (five or more years) assessing maxillary sinus floor augmentation. Int J Oral Maxillofac Surg. 2018 Jan;47(1):103-116. doi: 10.1016/j.ijom.2017.05.001. Epub 2017 May 22.
  23. Strauss, F.J., Stähli, A., Gruber, R. The use of platelet-rich fibrin to enhance the outcomes of implant therapy: A systematic review. Clin Oral Implants Res. 2018 Oct;29 Suppl 18:6-19. doi: 10.1111/clr.13275.
  24. Tajima, N., Ohba, S., Sawase, T., Asahima, I. Evaluation of sinus floor augmentation with simultaneous implant placement using platelet-rich-fibrin as sole grafting material. Int J Oral Maxillofac Implants 2013;28(1):77- 83.
  25. Tatullo M, Marrelli M, Cassetta M, Pacifici A, Stefanelli LV, Scacco S, Dipalma G, Pacifici L, Inchingolo F. Platelet Rich Fibrin (P.R.F.) in reconstructive surgery of atrophied maxillary bones: clinical and histological evaluations. Int J Med Sci. 2012;9(10):872-80 [doi: 10.7150/ijms.5119. Epub 2012 Nov 7].
  26. Wu IH, Bakhshalian N, Galaustian R, Naini RB, Min S, Freire M, Zadeh HH. Retrospective Analysis of the Outcome of Ridge Preservation with Anorganic Bovine Bone Mineral: Marginal Bone Level at Implants Placed Following Healing of Grafted Extraction Sockets. Int J Periodontics Restorative Dent. 2019 Jan/Feb;39(1):131-140. doi: 10.11607/prd.3308.
  27. Xuan, F., Lee, C.U., Son, J.S., jeong, S.M., Choi, B.H. A comparative study of the regenerative effect of sinus bone grafting with platelet-rich fibrin-mixed Bio-Oss® and commercial fibrin-mixed Bio-Oss®: an experimental study. J Craniomaxillofac Surg. 2014 Jun;42(4):e47-50 [ doi: 10.1016/j.jcms.2013.05.029. Epub 2013 Aug 2].
  28. You, J.S., Kim, S.G., Oh, J.S., Kim, J.S. Effects of Platelet-Derived Material (Platelet-Rich Fibrin) on Bone Regeneration. Implant Dent. 2019 Mar 8 [doi: 10.1097/ID.0000000000000877.
  29. Zhang, Y., Tangl, S., Huber, C. D., Lin, Y., Qiu, L., Raush-Fan, X. Effects of Choukroun’s platelet-rich-fibrin on bone regeneration in combination with deproteinized bovine bone mineral in maxillary sinus augmentation: a histological and histomorphometric study. J Craniomaxillofac Surg. 2012; 40 (4): 321 -8.
  30. Zhou, J., Li, X., Sun, X., Qi, M., Chi, M., Yin, L., Zhou, Y. Bone regeneration around immediate placed implant of molar teeth with autologous platelet-rich fibrin: Two case reports. Medicine (Baltimore). 2018 Nov;97(44):e13058. doi: 10.1097/MD.0000000000013058.

How to Cite

Silva, M. E. L. da ., Marrubio, M. de L. C., Silva, V. H. B. M. da, & Kassis, E. N. (2022). Major clinical findings of maxillary sinus surgery and the use of bio stimulators: a systematic review. MedNEXT Journal of Medical and Health Sciences, 3(S3). https://doi.org/10.54448/mdnt22S307